super structure

New answers and sure enough new mysteries in the study of genome architecture, after a project in Barcelona examined exactly how DNA is arranged in the fibrous molecular chains it forms while about its information-management business. Getting a good look is only feasible with super-resolution microscopy, and even then you need to get creative with the data analysis; but the DNA arrangement seems to relate directly to how well a cell might perform as a pluripotent stem cell. Good news for any structural biologists feeling sidelined by general genome hoopla. The announcement from ICFO last month; and my conversation with them about it for Optics.org.

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